Photodynamic Therapy for Ocular Diseases

Photodynamic Therapy in Ocular Oncology

Although introduced for the treatment of maculopathies, photodynamic therapy (PDT) is now largely used in some eye cancers treatment. The selective tissue damage with PDT is achieved by sequestration of the photosensitizer in the target tissue and focal activation of the photosensitizer by low energy directed light. In this way, it is possible to achieve the destruction of the tumor tissue by s...

Ocular changes after photodynamic therapy.

PURPOSE The aim of this study was to identify the changes in the primate visual system after a single session of photodynamic therapy (PDT) in an intact nonhuman primate retina. METHODS As part of a larger study, PDT (wavelength 689 nm, 50 J/cm2, 600 mW/cm2, 83 seconds, 4-mm spot size) with verteporfin (6 mg/m2 intravenous infusion) was performed in one eye each of two cynomolgus monkeys. Fun...

Photodynamic Therapy for Gynecological Diseases and Breast Cancer

Photodynamic therapy (PDT) is a minimally invasive and promising new method in cancer treatment. Cytotoxic reactive oxygen species (ROS) are generated by the tissue-localized non-toxic sensitizer upon illumination and in the presence of oxygen. Thus, selective destruction of a targeted tumor may be achieved. Compared with traditional cancer treatment, PDI has advantages including higher selecti...

Verteporfin photodynamic therapy of choroidal neovascularization secondary to ocular toxoplasmosis.

had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Financial Disclosure: None. Funding/Support: This study was supported in part by an unrestricted grant from Research to Prevent Blindness, New York, NY, and grant NEI EY02698 to Paul Kaufman, MD, from the National Institutes of Health, Bethesda, Md. Acknowle...

Is Photodynamic Therapy Effective in Treatment of Periodontal Diseases? A Review of Literature